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National Repository of Grey Literature

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The role of RNA-demethylase FTO in the regulation of cellular function and energy homeostasis Pohanová, Petra ; Telenský, Petr (advisor) ; Hlaváčková, Markéta (referee) Metyladenosin je nejčastější transkripční RNA. Nedávno bylo zjištěno, že modifikace může významným způsobem ovlivňovat další zpracování, transport a degradaci RNA a celkově je významným epigenetickým regulačním činitelem. demetylázu FTO, jejíž funkce se projevuje významnou regulační funkci v řízení metabolismu a udržování energetické homeostáze. demetylázy FTO může být příčinou různých patofyziologických stavů např. obezit Detailed record

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